LAG1 longevity assurance homolog 6; ceramide synthase 6 (CERS6, LASS6)

Function

• role in sphingolipid synthesis or its regulation
• glycosylation on Asn-18 is not necessary for function

Structure

• N-glycosylated
• contains 1 homeobox DNA-binding domain
• contains 1 TLC (TRAM/LAG1/CLN8) domain

Compartment

• nuclear membrane
• endoplasmic reticulum membrane
• multi-pass membrane protein (putative)

More general terms

• LAG1 longevity assurance homolog
• glycoprotein

Additional terms

• Lag1 (longevity assurance gene 1) transcription factor

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=253782
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:253782
• UniProt: http://www.uniprot.org/uniprot/Q6ZMG9.html