cytokeratin-39 (keratin, type-1 cytoskeletal 39, keratin-39, K39, type-1 hair keratin Ka35, KRT39, KA35)

Function

• may play a role in late hair differentiation

Structure

• heterotetramer of two type-1 & two type-2 keratins
• belongs to the intermediate filament family

Expression

• expressed in skin & scalp
• in the hair follicle, present in the upper hair cuticle & the upper cortex
• also present in the in the upper portion of beard hairs (at protein level)
• during differentiation of the hair, it is one of the last keratins expressed

More general terms

• cytokeratin, epithelial keratins or soft alpha-keratins

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3907
• UniProt: http://www.uniprot.org/uniprot/Q6A163.html