histidyl tRNA synthetase; histidine-tRNA ligase; HisRS (HARS, HRS)

Function

-..........-

ATP + L-histidine + tRNA(His)
            <-->
AMP + diphosphate + L-histidyl-tRNA(His)

Structure

• belongs to aminoacyl-tRNA synthetase-2 family
• contains 1 WHEP-TRS domain

Compartment

cytoplasm

Expression

brain, heart, liver & kidney

More general terms

• amino acyl tRNA synthetase-2

Additional terms

• histidine-tRNA ligase, mitochondrial; histidine-tRNA ligase-like; histidyl-tRNA synthetase; HisRS (HARS2, HARSL, HARSR, HO3)

Database

• UniProt: http://www.uniprot.org/uniprot/P12081.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3035
• OMIM: https://mirror.omim.org/entry/142810