histidine-tRNA ligase, mitochondrial; histidine-tRNA ligase-like; histidyl-tRNA synthetase; HisRS (HARS2, HARSL, HARSR, HO3)

Function

-..........-

ATP + L-histidine + tRNA(His)
        <-->
AMP + diphosphate + L-histidyl-tRNA(His)

Structure

• belongs to the class-II aminoacyl-tRNA synthetase family

Compartment

mitochondrial matrix

Expression

• expressed in heart, kidney, skeletal muscle > brain, liver

More general terms

• amino acyl tRNA synthetase-2
• mitochondrial protein
• phosphoprotein

Additional terms

• D-tyrosyl-tRNA(Tyr) deacylase 1 (HARS2, DTD1, C20orf88)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=23438
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:23438
• OMIM: https://mirror.omim.org/entry/600783
• UniProt: http://www.uniprot.org/uniprot/P49590.html