valyl tRNA synthetase (valine-tRNA ligase, ValRS, protein G7a, VARS, G7A, VARS2)

Function

• forms high-molecular-mass aggregates with elongation factor 1
• can be regulated by protein kinase C-dependent phosphorylation

ATP + L-valine + tRNA(Val)
           <-->
AMP + diphosphate + L-valyl-tRNA(Val)

Structure

• belongs to aminoacyl-tRNA synthetase-1 family
• contains 1 GST-like domain

More general terms

• amino acyl tRNA synthetase-1

Database

• UniProt: http://www.uniprot.org/uniprot/P26640.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7407
• OMIM: https://mirror.omim.org/entry/192150