microsomal glutathione S-transferase 3 (microsomal GST- 3, microsomal GST-III, MGST3)

Function

• also functions as a glutathione peroxidase

RX + glutathione = HX + R-S-glutathione

Structure

belongs to the MAPEG family

Compartment

microsome membrane

Expression

• predominantly expressed in heart, skeletal muscle, & adrenal cortex
• also found in brain, placenta, liver, kidney, pancreas, thyroid, testis & ovary
• lmost absent in lung, thymus & peripheral blood leukocytes

More general terms

• microsomal glutathione S-transferase

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:4259
• OMIM: https://mirror.omim.org/entry/604564
• UniProt: http://www.uniprot.org/uniprot/O14880.html