1-acyl-sn-glycerol-3-phosphate acyltransferase eta; 1-AGP acyltransferase 7; 1-AGPAT 7, lysophosphatidic acid acyltransferase eta; LPAAT-eta; acyltransferase-like 3 (AGPAT7, LPCAT4, AYTL3)

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Function

  • converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (putative)
  • de novo phospholipid biosynthesis, 2nd step
Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate
               <-->
CoA + 1,2-diacyl-sn-glycerol 3-phosphate

Structure

Compartment

endoplasmic reticulum membrane

Alternative splicing

named isoforms=3

Expression

More general terms

References

Database