tRNA-specific adenosine deaminase 1 (hADAT1, tRNA-specific adenosine-37 deaminase, ADAT1)

Function

• specifically deaminates adenosine-37 to inosine in tRNA-Ala
• binds 1 inositol hexakisphosphate (IP6) per subunit

Structure

• belongs to the ADAT1 family
• contains 1 A to I editase domain

Alternative splicing

named isoforms=2

Expression

• ubiquitously expressed

More general terms

• nucleoside deaminase

Database

• OMIM: https://mirror.omim.org/entry/604230
• UniProt: http://www.uniprot.org/uniprot/Q9BUB4.html