splicing factor arginine/serine-rich 12; serine-arginine-rich splicing regulatory protein 86; SRrp86; splicing regulatory protein 508; SRrp508 (SFRS12, SRRP86, SREK1)

Function

• regulation of alternative splicing
• modulates activity of other splicing factors
• inhibits splicing activity of SFRS1, SFRS2, SFRS6
• enhances splicing activity of SFRS3
• binds SFRS1, SFRS2, SFRS3, SFRS6
• interacts with spliceosome

Structure

homodimer

Compartment

nuclear

More general terms

• splicing factor arginine/serine-rich (SFRS)

Database

• UniProt: http://www.uniprot.org/uniprot/Q8WXA9.html