tripartite motif-containing protein 45; RING finger protein 99 (TRIM45 RNF99)

Function

• may act as a transcriptional repressor in MAP kinase signaling

Structure

• belongs to the TRIM/RBCC family
• contains 2 B box-type Zn+2 fingers
• contains 1 filamin repeat
• contains 1 RING-type Zn+2 finger

Compartment

cytoplasm. nucleus

Alternative splicing

named isoforms=2

Expression

• expressed in skeletal muscle, brain, heart & pancreas
• in 80-day old embryo, expressed in brain, lung, skeletal muscle, heart & intestine

More general terms

• tripartite motif-containing protein (trim protein)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=80263
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:80263
• OMIM: https://mirror.omim.org/entry/609318
• UniProt: http://www.uniprot.org/uniprot/Q9H8W5.html