granzyme H; cytotoxic T-lymphocyte proteinase; cathepsin G-like 2; CTSGL2; CCP-X; cytotoxic serine protease C; CSP-C (GZMH, CGL2, CTSGL2)

Function

• probably necessary for target cell lysis in cell-mediated immune responses

Structure

• belongs to the peptidase S1 family, Granzyme subfamily
• contains 1 peptidase S1 domain

Compartment

• cytoplasmic granule
• cytoplasmic granules of cytolytic T-lymphocytes

More general terms

• granzyme, cytotoxic T-cell protease; CTL tryptase; fragmentin
• glycoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/P20718.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2999
• OMIM: https://mirror.omim.org/entry/116831
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2999