peptidyl-prolyl cis-trans isomerase-like 3 (PPIase, Rotamase, cyclophilin-like protein PPIL3, cyclophilin J, CyPJ, PPIL3)

Function

• accelerates folding of proteins
• catalyzes cis-trans isomerization of proline imidic peptide bonds in oligopeptides
• may be involved in pre-mRNA splicing
• identified in the spliceosome C complex

Structure

• belongs to the cyclophilin-type PPIase family, PPIL3 subfamily
• contains 1 PPIase cyclophilin-type domain

Alternative splicing

named isoforms=2

Expression

• ubiquitous
• detected at low levels

More general terms

• cyclophilin

Component of

• spicesome C complex

Database

• UniProt: http://www.uniprot.org/uniprot/Q9H2H8.html