fucosyltransferase-8; alpha-(1,6)-fucosyltransferase; glycoprotein 6-alpha-L-fucosyltransferase; GDP-fucose-glycoprotein fucosyltransferase; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase; alpha1-6FucT (FUT8)
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Function
- catalyzes addition of fucose in alpha 1-6 linkage to 1st GlcNAc residue, next to the peptide chains in N-glycans
- glycosylation
Structure
- belongs to the glycosyltransferase 23 family
- contains 1 SH3 domain
Compartment
- Golgi apparatus, Golgi stack
- membrane-bound form in trans cisternae of Golgi
Alternative splicing
named isoforms=2
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/Q9BYC5.html
- ↑ GGDB; Note: glycogene database http://riodb.ibase.aist.go.jp/rcmg/ggdb/homolog?cat=symbol&symbol=FUT8
- ↑ Functional glycomics gateway - GTase, fucosyltransferase 8 http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewglycoEnzyme.jsp?gbpId=gt_hum_605