inositol pentaphosphate-1-phosphatase or inositol polyphosphate-1-phosphatase

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Function

  • phosphatidylinositol signaling pathway
  • allegedly requires ATP
1D-myo-inositol 1,4-bisphosphate + H2O
         <-->
1D-myo-inositol 4-phosphate + phosphate

Cofactor: Mg+2]

Inhibition:

  • inhibited by Li+

Structure

Expression

More general terms

References

  1. Menniti FS, Oliver KG, Putney JW Jr, Shears SB. Inositol phosphates and cell signaling: new views of InsP5 and InsP6. Trends Biochem Sci. 1993 Feb;18(2):53-6. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8387704
  2. UniProt http://www.uniprot.org/uniprot/P49441.html

Database