inositol pentaphosphate-1-phosphatase or inositol polyphosphate-1-phosphatase
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Function
- phosphatidylinositol signaling pathway
- allegedly requires ATP
1D-myo-inositol 1,4-bisphosphate + H2O <--> 1D-myo-inositol 4-phosphate + phosphate
Cofactor: Mg+2]
Inhibition:
- inhibited by Li+
Structure
- monomer (putative)
- belongs to the inositol monophosphatase family
Expression
- ubiquitously expressed
- highest levels in pancreas & kidney
More general terms
References
- ↑ Menniti FS, Oliver KG, Putney JW Jr, Shears SB. Inositol phosphates and cell signaling: new views of InsP5 and InsP6. Trends Biochem Sci. 1993 Feb;18(2):53-6. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8387704
- ↑ UniProt http://www.uniprot.org/uniprot/P49441.html