11-beta hydroxysteroid dehydrogenase-2 (corticosteroid 11-beta-dehydrogenase isozyme 2, 11-DH2, 11-beta-hydroxysteroid dehydrogenase type 2, 11-beta-HSD2, NAD-dependent 11-beta-hydroxysteroid dehydrogenase, HSD11B2 HSD11K)

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Function

11-beta-hydroxysteroid + NAD+ <--> 11- oxosteroid + NADH

Inhibition:

  • inhibited by glycyrrhetinic acid (derived from liquorice), carbenoloxone & 11-alpha-OH-progesterone

Structure

Compartment

microsome

Expression

Pathology

More general terms

References

Database