beta-1,4-galactosyltransferase 3; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 3; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 3 (B4GALT3)

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Function

UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide
  => UDP + beta-D-galactosyl-1,4-N-acetyl-beta-D- glucosaminylglycopeptide
UDP-galactose + N-acetyl-D-glucosamine
  => UDP + N-acetyllactosamine

Cofactor: Mn+2 (putative)

Kinetic parameters:

  • KM=63 uM for GlcNAc-B-S-pNP

Structure

belongs to the glycosyltransferase 7 family

Compartment

  • Golgi stack membrane
  • trans cisternae of Golgi stack

Alternative splicing

named isoforms=2

Expression

More general terms

References

Database