RNA exonuclease 4; exonuclease XPMC2; hPMC2; prevents mitotic catastrophe 2 protein homolog (REXO4, PMC2, XPMC2H)

Function

• can bind ESR1 & ESR2
• interaction abrogated by estrogen & augmented by tamoxifen

Structure

• belongs to the REXO4 family.
• contains 1 exonuclease domain

Compartment

nucleus, nucleolus

Alternative splicing

named isoforms=2

More general terms

• exonuclease

Database

• OMIM: https://mirror.omim.org/entry/602930
• UniProt: http://www.uniprot.org/uniprot/Q9GZR2.html