chromosomal translocation t5q35:11p15.5 (childhood AML)
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Introduction
Translocation associated with childhood acute myeloid leukemia, & myelodysplastic syndrome in adults. The translocation generates a NUP98-NSD1 fusion product.
More general terms
Additional terms
- acute myeloid leukemia (AML)
- nuclear pore complex protein Nup98 (nucleoporin Nup98)
- nuclear receptor binding SET domain containing protein 1; histone-lysine N-methyltransferase, H3 Lys36 & H4 Lys20 specific; H3-K36-HMTase; H4-K20-HMTase; NR-binding SET domain containing protein; androgen receptor-associated coregulator 267 (NSD1, ARA267)