chromosomal insertion ins(12;8)(p11;p11p22)
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Introduction
chromosomal insertion ins(12;8)(p11;p11p22) involving FGFR1OP2 with FGFR1 may be a cause of stem cell myeloproliferative disorder, fusion protein FGFR1OP2-FGFR1 may exhibit constitutive kinase activity & be responsible for the transforming activity