eunuchism

Introduction

Testicular failure.

Etiology

• congenital
• acquired

Clinical manifestations

• prepubertal
  • hypoplastic penis & testis
  • thin smooth skin
  • failure of the voice to deepen
  • female eschutcheon of pubic hair
  • absence of beard
  • poor muscular development
  • long limbs
  • broad hips
  • gynecomastia
• postpubertal
  • testicular atrophy
  • pallor

Laboratory

• urine chemistries:
• normal or low androgens & 17-ketosteroids
• high urinary gonadotropins

Radiology

delayed closure of epiphyses

More general terms

• gonadal disorder

Additional terms

• fertile eunuch syndrome