capillary leak syndrome (CLS)

Etiology

• paraproteinemia
• all-trans-retinoic acid-induced differentiation syndrome
• sargramostim
• aldesleukin
• dinutuximab
• moxetumomab

Clinical manifestations

• dyspnea
• edema, including facial edema & peripheral edema
• hypotension
• reduced organ perfusion
• may result in death

More general terms

• syndrome
• capillary disease

Additional terms

• capillary fragility