coccidioidin skin testing

Indications

• intradermal skin test used in the diagnosis of coccidioidomycosis
• differentiation of coccidioidomycosis from histoplasmosis, sarcoidosis, other mycotic or mycobacterial infection
• may be used to assess anergy in endemic areas

Dosage

Injection: 1:100 (1 mL)

Procedure

• 0.1 mL of a 1:100 dilution of Spherulin (coccidioidin) in the flexor suface of the forearm
• a 5 mm or more induration is considered positive
• erythema without induration is considered negative
• test is read at 24 & 48 hours
• a positive reaction indicateds past or present infection with Coccidioides immitis
• a negative test indicated the individual
  • has not been sensitized to the coccidioidin antigen
  • the individual is anergic or has lost sensitivity

More general terms

• skin testing

Additional terms

• coccidioidomycosis