lead time bias

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Introduction

One of 2 major biasis that complicate observational studies on screening tests.

Lead time bias occurs when the time from onset of symptoms to death is not changed by diagnosis in asymptomatic individuals, although the length of life appears longer for those cases with an early diagnosis.

More general terms

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998