C elegans DAF2 gene

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Introduction

Mutations in the C elegans gene DAF2 reduce Gompertz rate of mortality. The gene encodes a homolog of the insulin receptor.

More general terms

Additional terms

References

  1. Mobbs C, Molecular & biological factros in aging In: Geriatric Medicine: An Evidence-Based Approach, 4th ed, Cassel CK et al (eds), Springer-Verlag, New York, 2003
  2. Kimura KD et al, daf-2, an insulin receptor-like gene that regulates longevity and diapause Caenorhabditis elegans. Science 1997 277:942