HIV-associated neutropenia

Etiology

• bone marrow infiltration
  • granulomatous infectious process
  • lymphoma
• pharmaceutical agents
  • nucleoside analogues
  • trimethoprim-sulfamethoxazole
  • ganciclovir
  • chemotherapy for treatment of:
    • lymphoma
    • Kaposi's sarcoma

Management

• granulocyte colony-stimulating factor (G-CSF)
  • neutrophils count < 500/mm3
  • continue therapy until neutrophil count > 1000/mm3

More general terms

• HIV1/AIDS-associated hematologic disorder
• neutropenia