coagulation factor VII autoantibody

Introduction

Autoantibody to factor VII enhances clearance of factor VII from the circulation.

In vitro coagulation tests correct with addition of normal plasma because the autoantibody does not interact with the active site of an enzyme.

More general terms

• autoantibody
• coagulation factor antibody

Additional terms

• coagulation factor VII inhibitor in plasma
• coagulation factor VII; proconvertin; serum prothrombin conversion accelerator; SPCA; Eptacog alfa; contains: factor VII light chain; factor VII heavy chain (F7)