von Willebrand factor (VWF) autoantibody

Introduction

Autoantibody to vWF enhances clearance of vWF from the circulation.

In vitro coagulation tests correct with addition of normal plasma because the autoantibody does not interact with the active site of an enzyme.

More general terms

• autoantibody
• coagulation factor antibody

Additional terms

• coagulation factor X; Stuart factor; Stuart-Prower factor; contains: factor X light chain; factor X heavy chain; activated factor Xa heavy chain (F10)