Roseburia

Introduction

• genus of butyrate-producing, Gram-positive anaerobic bacteria

Epidemiology

• inhabit the human colon

Pathology

• Faecalibacterium & Roseburia are consistently reduced in MCI & AD in a small number of studies
• Roseburia may have a beneficial effect on inflammatory bowel disease, alcoholic fatty liver, colorectal cancer, & metabolic syndrome

Laboratory

• microscopic
  • curved-rod shape
  • uses its flagella for mobility

Comparative biology

• increased abundance of Roseburia is associated with weight loss & reduced glucose intolerance in mice

More general terms

• Eubacteriales (Clostridiales)