Endovascular Aneurysm Repair (EVAR) trial
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Introduction
Design:
- male & female patients aged at least 60 years of age
- AAA diameter measuring at least 5.5 cm on a computed tomography (CT)
- two trials, 900 & 280 patients
- recruitment begun 10/99
open repair vs endovascular aneurysm repair
Endpoints:
- mortality
- quality of life
- durability
- cost-effectiveness
Results:
- endovascular repair associatated with:
- lower 30 day mortality (1.7% vs 4.7%)
- shorter mean hospital stay (7 days vs 12 days)
- 2% of endovascular repairs converted to open repairs
- 3% in both both groups required 2nd surgery
- 2-year survival no better than open repair & is more costly[3]
More general terms
Additional terms
References
- ↑ Brown LC, Epstein D, Manca A, Beard JD, Powell JT, Greenhalgh RM. The UK Endovascular Aneurysm Repair (EVAR) trials: design, methodology and progress. Eur J Vasc Endovasc Surg. 2004 Apr;27(4):372-81. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15015186
- ↑ Greenhalgh RM, Brown LC, Kwong GP, Powell JT, Thompson SG; EVAR trial participants. Comparison of endovascular aneurysm repair with open repair in patients with abdominal aortic aneurysm (EVAR trial 1), 30-day operative mortality results: randomised controlled trial. Lancet. 2004 Sep 4;364(9437):843-8. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15351191
- ↑ 3.0 3.1 Journal Watch 25(15):123, 2005
EVAR trial participants. Endovascular aneurysm repair and outcome in patients unfit for open repair of abdominal aortic aneurysm (EVAR trial 2): randomised controlled trial. Lancet. 2005 Jun 25;365(9478):2187-92. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15978926 [PubMed - in process]
EVAR trial participants. Endovascular aneurysm repair versus open repair in patients with abdominal aortic aneurysm (EVAR trial 1): randomised controlled trial. Lancet. 2005 Jun 25;365(9478):2179-86. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15978925