asymptomatic carotid artery stenosis (ACAS) study

Introduction

Design:

• 1659 patients, age 40-79
• 60-99% carotid stenosis
• median 2.7 year follow-up
• primary endpoint: 5 year risk of ipsilateral stroke, perioperative stroke or death

Results:

• endpoint reached in
  • 11% of medically treated patients
  • 4% of surgically treated patients

gender difference

• Men 12% medical vs 4% surgical
• Women 9% medical vs 7% surgical

More general terms

• clinical trial