Dutch Randomized Endovascular Aneurysm Management trial (DREAM trial)

Introduction

Design:

• 345 patients with abdominal aortic aneurysm > 5 cm in diameter randomized to endovascular vs open repair

primary endpoint: 30 day operative mortality or moderate-severe complication

Results:

• primary endpoint reached in 24% of open repair vs 18% of endovascular repair patients
• procedure related mortality was 4.6% in open repair group vs 1.2% in endovascular repair group
• cardiac & pulmonary complications occurred significantly more often after open repair
• vascular complications occurred more often after endovascular repair

More general terms

• clinical trial

Additional terms

• Diabetes REduction Assessment with ramipril & rosiglitazone Medication (DREAM) study