Combined Angiolasty & Pharmacologic Intervention versus Thromboylisis ALone in Acute Mycocardial Infarction (CAPITAL AMI) study
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Introduction
Design:
- 170 patients with STEMI
Treatmemt:
- tenecteplase-facilitated angioplasty vs tenecteplase alone
Primary endpoint:
- composite death, reinfarction, recurrent unstable angina or stroke at 6 months
Results: primary endpoints reached in:* 12% of tenecteplase-facilitated angioplasty group 21% of tenecteplase alone group
* difference significant due to reduction in recurrent unstable angina (8% vs 21%) & trend towards reduction in reinfarction (5% vs 15%) no difference in rates of stroke or death
No differences is major bleeding (8% vs 7%)
More general terms
Additional terms
References
- ↑ Le May MR, Wells GA, Labinaz M, Davies RF, Turek M, Leddy D, Maloney J, McKibbin T, Quinn B, Beanlands RS, Glover C, Marquis JF, O'Brien ER, Williams WL, Higginson LA. Combined angioplasty and pharmacological intervention versus thrombolysis alone in acute myocardial infarction (CAPITAL AMI study). J Am Coll Cardiol. 2005 Aug 2;46(3):417-24. PMID: https://www.ncbi.nlm.nih.gov/pubmed/16053952