factor V Quebec

Pathology

• proteolytic degradation of multimerin-1 within platelet alpha granules

Genetics

• autosomal dominant
• deficiency in multimerin-1

Clinical manifestations

• bleeding disorder

More general terms

• genetic syndrome (multisystem disorder)
• genetic disease of the blood/bone marrow

Additional terms

• coagulation factor V; activated protein C cofactor; proaccelerin, labile factor; contains: coagulation factor V heavy chain; coagulation factor V light chain (F5)