hypotrichosis simplex of scalp (Spanish type)

Genetics

• autosomal dominant
• associated with defects in CDSN gene

Clinical manifestations

• isoloated alopecia
  • affected individuals have normal hair in early childhood
  • progressive loss of scalp hair beginning in the middle of the 1st decade
  • almost complete baldness by the 3rd decade of life

More general terms

• hypotrichosis
• scalp disorder

Database

• OMIM: https://mirror.omim.org/entry/146520