mirror-image polydactyly of hands & feet without other anomalies

Epidemiology

• very rare

Genetics

• most cases are sporadic
• rare parent-child transmissions, autosomal
• associated with translocation t(2;14)(p23.3;q13) involving MIPOL1

Clinical manifestations

• mirror-image duplication of digits
• occasionally associated with
  • dimelia of the ulna & fibula
  • tibial &/or fibular hypoplasia
  • nasal abnormality
  • other malformations

More general terms

• genetic syndrome (multisystem disorder)
• congenital anomaly (birth defect)