aminoglycoside-induced deafness

Etiology

• aminoglycoside toxicity

Genetics

• associated with A1555G mutation in the mitochondrial 12S rRNA
• variations in TFB1M may affect severity of deafness
• Val-250 polymorphism in GTPBP3 gene may affect severity of deafness

Clinical manifestations

• variable degree of deafness

More general terms

• deafness

Additional terms

• aminoglycoside antibiotic

Database

• OMIM: https://mirror.omim.org/entry/580000