azelaic acid (Azelex, Finacea, Finevin)

Indications

• topical agent for adjuctive treatment of:
  • acne
  • rosacea

Contraindications

pregnancy category: B

safety in lactation: ?

Dosage

• apply BID.

Finevin, Azelex: 20%

Finacea Gel 15% less acidic than Finevin, Azelex

Adverse effects

• local irritation

Mechanism of action

• tyrosinase inhibitor
• cytotoxic to melanocytes

More general terms

• dermatologic agent

Component of

• azelaic acid/tranexamic acid
• azelaic acid/folic acid/nicotinamide/pyridoxine/zinc oxide

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=2266