Lyme (Borrelia burgdorferi) vaccine (Lymerix, OspA protein)

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[1][2][3][4]

Indications

  • prevention of Lyme disease Off the market in 2002 due to low demand.

Dosage

  • doses at 0, 1 & 2-6 months
  • booster at 12 months & yearly therafter

Pharmacokinetics

  • 50% effective after 2nd dose
  • 78% effective after 3rd dose

Adverse effects

Mechanism of action

  • stimulation of antibody production that work in the gut of the offending tick
  • contains synthetic form of OspA protein

More general terms

References

  1. ↑ Prescriber's Letter 7(2):7, Feb. 2000
  2. ↑ Prescriber's Letter 8(3):14 2001
  3. ↑ Prescriber's Letter 9(4):21 2002
  4. ↑ RxList http://www.rxlist.com/lymerix-drug.htm
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