trontinemab
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Introduction
a human transferrin receptor 1-directed Brainshuttle module
More general terms
References
- ↑ Grimm HP, Schumacher V, Schafer M et al Delivery of the Brainshuttle amyloid-beta antibody fusion trontinemab to non-human primate brain and projected efficacious dose regimens in humans. MAbs. 2023 Jan-Dec;15(1):2261509. PMID: https://pubmed.ncbi.nlm.nih.gov/37823690 PMCID: PMC10572082 Free PMC article.
- ↑ Muliaditan M, van Steeg TJ, Avery LB et al Translational minimal physiologically based pharmacokinetic model for transferrin receptor-mediated brain delivery of antibodies. MAbs. 2025 Dec;17(1):2515414. PMID: https://pubmed.ncbi.nlm.nih.gov/40568753 PMCID: PMC12203839 Free PMC article.