drug interaction(s) of palbociclib with proton pump inhibitors
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Drug interactions
- concurrent use of proton pump inhibitor with palbociclib is associated with a shorter survival[1]
- 2-year overall survival 69.5% vs 89.3%[1]
More general terms
References
- ↑ 1.0 1.1 1.2 Bassett M PPIs Linked to Worse Outcomes With Widely Used Breast Cancer Drug. Concomitant use of proton pump inhibitors with palbociclib associated with shorter survival. MedPage Today July 21, 2023 https://www.medpagetoday.com/hematologyoncology/breastcancer/105604
Lee JE, Kwon SH, Kwon S et al Concomitant Use of Proton Pump Inhibitors and Palbociclib Among Patients With Breast Cancer. JAMA Netw Open. 2023;6(7):e2324852 PMID: https://www.ncbi.nlm.nih.gov/pubmed/37477917 PMCID: PMC10362477 Free PMC article https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2807485