RNA polymerase II subunit A C-terminal domain phosphatase SSU72 like protein 5; RNA polymerase II subunit A C-terminal domain phosphatase SSU72L5; CTD phosphatase SSU72L5 (SSU72L5)

Function

• protein phosphatase
• catalyzes dephosphorylation of the C-terminal domain of RNA polymerase II
• plays a role in RNA processing & termination

H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] + phosphate

H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate

Structure

belongs to the SSU72 phosphatase family,

Compartment

nucleus

More general terms

• phosphoprotein phosphatase
• nuclear protein

Database

• UniProt: http://www.uniprot.org/uniprot/A0A1W2PQ64.html