perfluorohexyloctane (Miebo)

^[1]^[2]

Indications

used as an internal tamponade agent in surgery for complicated retinal detachments^[1]
treatment of dry eyes^[2]

Solution: 1 g/mL

liquid semifluorinated alkane that is heavier than water^[1]
increases tear film thickness & lipid layer thickness in dry eye syndrome
- prevents evaporation of tears through stabilization of the lipid layer^[2]

↑ ^1.0 ^1.1 ^1.2 Kirchhof B, Wong D, Van Meurs J et al Use of perfluorohexyloctane as a long-term internal tamponade agent in complicated retinal detachment surgery. Am J Ophthalmol. 2002. 01/01 PMID: https://www.ncbi.nlm.nih.gov/pubmed/11755844
↑ ^2.0 ^2.1 ^2.2 Schmidl D, Bata AM, Szegedi S et al Influence of Perfluorohexyloctane Eye Drops on Tear Film Thickness in Patients with Mild to Moderate Dry Eye Disease: A Randomized Controlled Clinical Trial. J Ocul Pharmacol Ther. 2020 Apr;36(3):154-161 PMID: https://www.ncbi.nlm.nih.gov/pubmed/31895638