LDL triglycerides in serum/plasma
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Clinical significance
- elevated levels associated with increased risk of atherosclerotic cardiovascular disease
- increased risk not entirely statistically explained by serum apolipoprotein B levels
- may represent LDL remnants
Methods
- NMR spectroscopy
- direct automated assay (nor FDA-approved in U.S.)
Management
- statins lower serum LDL cholesterol & serum triglycerides & perhaps LDL remnants
Notes
- not clear if relationship to VLDL cholesterol in serum or triglycerides in serum
More general terms
References
- ↑ Kirkner RM LDL Cholesterol Triglycerides 'Robust' ASCVD Risk Marker. Medscape. Jan 12, 2023 https://www.medscape.com/viewarticle/986880
Balling M, Afzal S, Davy Smith G et al Elevated LDL Triglycerides and Atherosclerotic Risk. J Am Coll Cardiol. 2023. 81(2):136-152 PMID: https://www.ncbi.nlm.nih.gov/pubmed/36631208 https://www.sciencedirect.com/science/article/abs/pii/S0735109722073065
Duell PB. Triglyceride-Rich Lipoproteins and Atherosclerotic Cardiovascular Disease Risk. J Am Coll Cardiol. 2023 Jan 17;81(2):153-155. PMID: https://www.ncbi.nlm.nih.gov/pubmed/36631209