remdesivir analogue VV116

Indications

• oral treatment of Covid-19

* prelimary results suggest efficacy similar to Paxlovid

Dosage

• 600 mg PO every 12 hours on day 1
• 300 mg PO every 12 hours on days 2 through 5

Adverse effects

• dysgeusia (3.6% vs 25% with Paxlovid)
• hypertriglyceridemia (11% vs 21% with Paxlovid)
• hyperlipidemia (3.1% vs 9.6% with with Paxlovid)

Mechanism of action

• deuterated remdesivir hydrobromide

More general terms

• antiviral agent