Reinke space

Structure

• loose connective tissue subjacent to the basement membrane of squamous-lined true vocal fold
• it is devoid of glandular tissue & lymphatic channels

Pathology

• it is prone to react to trauma, either due to smoke, excessive phonation, or other trauma
• due to lack of lymphatic channels, edema with increased vascularization, known as Reinke edema may occur may manifest clinically as a polypoid projection into the airway.

More general terms

• connective tissue

Component of

• larynx