cold analgesia

Indications

• targeted & reversible blocking of peripheral nerve activity for treating pain

Mechanism of action

• soft, miniaturized, implantable cooler temporarily blocks nerve conduction using a liquid-to-gas phase transition as the cooling mechanism
• nerve cuff with a microfluidic channel carrying a microliter volume of bioinert coolant
• thermal thin-film sensor integrated within the cuff enables temperature monitoring in real time, enabling closed-loop control.
• the nerve block by the coolant prevents afferent tramsmission of pain signals

More general terms

• cold therapy
• analgesia