delta-delta

Introduction

-..........-

([Na+] - [Cl-] - [HCO3-])/(22* -[HCO3-])

* anion gap (measured - normal) / bicarbonate (normal - measured)

Reference interval

• 1-2

Increases

• > 2: consider concurrent metabolic acidosis

Decreases

• < 1: consider concurrent normal anion gap metabolic acidosis

Notes

• respiratory compensation for metabolic acidosis is 1.5 x [[[A18927|HCO3-]]] + 8

Components

• anion gap
• bicarbonate (HCO3-) in serum