urine telomerase reverse transcriptase promotor gene mutation (uTERTpm)

Indications

• detection of bladder cancer

* detectable years before the clinical diagnosis of bladder cancer

Principle

• detects mutations in the promoter of the TERT gene

Clinical significance

• TERT promoter mutations have been detected in 60-85% in all stages & grades of bladder cancers

More general terms

• urine chemistry test
• DNA (genetic) testing