disease interaction(s) of chronic hypertension with Alzheimer's disease (AD)
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Management
- intensive lowering of blood pressure (SPRINT target) associated with small decrease in hippocampal volume vs JNC8 target
- no other MRI biomarkers of AD differed between treatments[1]
More general terms
References
- ↑ 1.0 1.1 George J Can Managing Blood Pressure Slow Alzheimer's disease? PRINT MIND imaging findings muddy the picture. https://www.medpagetoday.com/neurology/alzheimersdisease/91520
Nasrallah IM et al Association of intensive vs standard blood pressure control with magnetic resonance imaging biomarkers of Alzheimer disease: secondary analysis of the SPRINT MIND randomized trial. JAMA Neurol 2021. March 8 PMID: https://www.ncbi.nlm.nih.gov/pubmed/33683313
Landau S, Harrison T. A link between cardiovascular risk management and Alzheimer disease is still elusive. JAMA Neurol 2021. March 8 PMID: https://www.ncbi.nlm.nih.gov/pubmed/33683302