Laugier-Hunziker syndrome

Epidemiology

• rare, > 100 cases described
• most cases in Europe France, Italy < U.S., U.K.

Genetics

• sporadic

Clinical manifestations

• similar mucocutaneous features to Peutz-Jeghers syndrome without systemic manifestations
• flat brown marks on the lips & inside the mouth
• brown stripes on the nails common

* images

Differential diagnosis

• Peutz-Jegher syndrome

Management

• benign disorder, no treatment indicated
• Laser therapy for bothersome or difiguring lesions

More general terms

• mucosal disease
• melanonychia; longitudinal melanonychia; melanonychia striata
• syndrome